Document and Entity Information Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Amendment Description Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Filer Category Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Period Focus CONDENSED CONSOLIDATED BALANCE SHEETS Assets [Abstract] ASSETS Assets, Current [Abstract] Current Assets: Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents at End of Period Cash and Cash Equivalents at Beginning of Period Cash and Cash Equivalents Available-for-sale Securities, Debt Securities, Current Marketable Securities Fair Value Accounts and Other Receivables, Net, Current Accounts and Other Receivables Prepaid Expense and Other Assets, Current Prepaid and Other Current Assets Assets, Current Total Current Assets Property, Plant and Equipment, Net Property and Equipment, Net Intangible Assets, Net (Excluding Goodwill) Intangible Assets, Net Intangible Assets, Net (Excluding Goodwill) Other Assets, Noncurrent Other Assets Goodwill Goodwill Assets Total Assets Liabilities and Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities, Current [Abstract] Current Liabilities: Accounts Payable, Current Accounts Payable Accrued Liabilities, Current Accrued Expenses Other Liabilities, Current Less Current Portion Current Portion of Long-Term Liabilities Liabilities, Current Total Current Liabilities Deferred Revenue, Current Current Portion of Deferred Revenue Convertible Subordinated Debt, Current Convertible Subordinated Debt Secured Debt, Current Current Portion of Term Loan Other Liabilities, Noncurrent Other Long-Term Liabilities Long-Term Portion Liabilities Total Liabilities Commitments and Contingencies. Commitments and Contingent Liabilities Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity: Preferred Stock, Value, Issued Convertible Preferred Stock, $.01 Par Value; 3,000,000 Shares Authorized; No Shares Issued and Outstanding at June 30, 2014 and December 31, 2013 Common Stock, Value, Issued Common Stock, $.001 Par Value; 297,000,000 Shares Authorized; 89,396,160 and 89,246,832 Shares Issued and Outstanding at June 30, 2014 and December 31, 2013, respectively Additional Paid in Capital, Common Stock Additional Paid-In Capital Accumulated Other Comprehensive Income (Loss), Net of Tax Balance at the end of the period Balance at the beginning of the period Accumulated Other Comprehensive Income Retained Earnings (Accumulated Deficit) Accumulated Deficit Stockholders' Equity Attributable to Parent Total Stockholders' Equity Liabilities and Equity Total Liabilities and Stockholders' Equity Deferred Revenue, Noncurrent Deferred Revenue Convertible Subordinated Debt, Noncurrent Convertible Subordinated Debt Secured Long-term Debt, Noncurrent Term Loan, less Current Portion Preferred Stock, Par or Stated Value Per Share Convertible Preferred Stock, Par Value (in dollars per share) Preferred Stock, Shares Authorized Convertible Preferred Stock, Shares Authorized Preferred Stock, Shares Issued Convertible Preferred Stock, Shares Issued Preferred Stock, Shares Outstanding Convertible Preferred Stock, Shares Outstanding Common Stock, Par or Stated Value Per Share Common Stock, Par Value (in dollars per share) Common Stock, Shares Authorized Common Stock, Shares Authorized Common Stock, Shares, Issued Common Stock, Shares Issued Common Stock, Shares, Outstanding Common Stock, Shares Outstanding CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Revenues [Abstract] REVENUE: This element represents revenue from product development and licensing agreements. Revenue from Product Development and Licensing Agreements Product Development and Licensing Agreements This element represents revenue earned during the period arising from products sold or services provided under the terms of a contract. Also include revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. Revenue from Contracts and Grants Contracts and Grants Royalty Revenue Product Royalties Revenues Total Revenue Costs and Expenses [Abstract] OPERATING EXPENSE: Research and Development Expense Research and Development Royalty Expense Royalty General and Administrative Expense General and Administrative Amortization of Intangible Assets Amortization of Acquired Intangible Assets Amortization of Intangible Assets Costs and Expenses Total Operating Expense Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property Gain on Sale of Assets Operating Income (Loss) Operating Loss Interest and Other Income Investment and Other Income, Net Interest Expense Interest Expense Net Income (Loss) Available to Common Stockholders, Basic Net Loss Net Loss Earnings Per Share, Basic and Diluted Basic and Diluted Net Loss Per Common Share (Note 3) (in dollars per share) Weighted Average Number of Shares Outstanding, Basic and Diluted Shares Used in Calculating Basic and Diluted Net Loss per Share (Note 3) (in shares) Comprehensive Loss COMPREHENSIVE LOSS: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other Comprehensive (Loss) Income: Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Foreign Currency Translation Adjustments Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Unrealized (Loss) Gain on Marketable Securities Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive Loss CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Cash Flows from Operating Activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities: Depreciation, Depletion and Amortization Depreciation and Amortization Accretion (Amortization) of Discounts and Premiums, Investments Amortization and Premium of Marketable Securities Gain (Loss) on Disposition of Property Plant Equipment Gain (Loss) on Sales or Disposal of Assets Share-based Compensation Stock-Based Compensation Expense Amortization of Debt Discount (Premium) Non-Cash Interest Expense Increase (Decrease) in Operating Capital [Abstract] Changes in Operating Assets and Liabilities: Increase (Decrease) in Accounts and Other Receivables Accounts and Other Receivables Increase (Decrease) in Prepaid Expense and Other Assets Prepaid and Other Current Assets Increase (Decrease) in Other Operating Assets Other Assets Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts Payable and Accrued Expenses Increase (Decrease) in Other Operating Liabilities Other Liabilities Increase (Decrease) in Deferred Revenue Deferred Revenue Other Noncash Income Tax Expense Non-Cash Tax Benefit Marketable Securities, Gain (Loss) Realized Gain on Sales and Maturities of Marketable Securities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operations Net Cash Used in Operating Activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Cash Flows from Investing Activities: Proceeds from Sale and Maturity of Marketable Securities Sales and Maturities of Marketable Securities Payments to Acquire Marketable Securities Purchases of Marketable Securities Payments to Acquire Property, Plant, and Equipment Acquisition of Property and Equipment Proceeds from Sale of Productive Assets Proceeds from Sales or Disposal of Assets Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net Cash Used in Investing Activities Cash Acquired from Acquisition Cash Acquired in the CuraGen acquisition Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Cash Flows from Financing Activities: Proceeds from Issuance of Common Stock Net proceeds from sale of common stock Net Proceeds from Stock Issuances Proceeds from Stock Plans Proceeds from Issuance of Stock from Employee Benefit Plans Repayments of Secured Debt Payments of Term Loan Repayments of Other Long-term Debt Payments of Other Liabilities Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net Cash Provided by Financing Activities Repayments of Subordinated Debt Related Party Loan Due to Medarex Proceeds from Issuance of Long-term Debt (Payments) Issuance of Term Loan Repayments of Convertible Debt Payment of Convertible Subordinated Debt Effect of Exchange Rate on Cash and Cash Equivalents, Continuing Operations Effect of Exchange Rate Changes on Cash and Cash Equivalents Net Cash Provided by (Used in) Continuing Operations Net (Decrease) Increase in Cash and Cash Equivalents Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental Disclosure of Non-Cash Flow Information Stock Granted, Value, Share-based Compensation, Net of Forfeitures Shares Issued to Executive Officers Supplemental Cash Flow Information [Abstract] Supplemental Disclosure of Cash Flow Information Interest Paid Cash Paid for Interest Basis of Presentation Basis of Accounting [Text Block] Basis of Presentation Significant Accounting Policies Significant Accounting Policies [Text Block] Significant Accounting Policies Net Loss Per Share Earnings Per Share [Text Block] Net Loss Per Share Comprehensive Income (Loss) Note [Text Block] Comprehensive Loss Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Marketable Securities Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Intangible Assets and Goodwill Goodwill and Intangible Assets Disclosure [Text Block] Intangible Assets and Goodwill Other Long-Term Liabilities Other Liabilities Disclosure [Text Block] Other Long-Term Liabilities Stockholders' Equity Stockholders' Equity Note Disclosure [Text Block] Stockholders' Equity Stock-Based Compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Income Taxes Income Tax Disclosure [Text Block] Income Taxes New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Use of Estimates, Policy [Policy Text Block] Use of Estimates Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Marketable Securities, Policy [Policy Text Block] Marketable Securities Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk and of Significant Customers and Suppliers Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment Business Combinations Policy [Policy Text Block] Business Combinations Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block] Intangible Assets Goodwill and Intangible Assets, Goodwill, Policy [Policy Text Block] Goodwill Impairment or Disposal of Long-Lived Assets, Including Intangible Assets, Policy [Policy Text Block] Impairment of Long-Lived Assets Revenue Recognition, Policy [Policy Text Block] Revenue Recognition Research and Development Expense, Policy [Policy Text Block] Research and Development Expenses Disclosure of accounting policy for patent costs. Patent Costs Policy [Text Block] Patent Costs Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block] Stock-Based Compensation Foreign Currency Transactions and Translations Policy [Policy Text Block] Foreign Currency Translation Income Tax, Policy [Policy Text Block] Income Taxes Comprehensive Income, Policy [Policy Text Block] Comprehensive Loss Earnings Per Share, Policy [Policy Text Block] Net Loss Per Share Disclosure of accounting policy for recognition of income due to transactions that are not part of on-going operations. Other Income [Policy Text Block] Other Income Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Summary of changes in accumulated other comprehensive income by component Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of financial assets subject to fair value measurements Schedule of Available-for-sale Securities Reconciliation [Table Text Block] Summary of marketable securities Schedule of Intangible Assets and Goodwill [Table Text Block] Schedule of intangible assets, net of accumulated amortization, and goodwill Tabular disclosure of other long-term liabilities, not separately disclosed on the balance sheet. Schedule of Other Long Term Liabilities [Table Text Block] Schedule of Other long-term liabilities Schedule of Long-term Debt Instruments [Table] Long-term Debt, Type [Axis] Longterm Debt Type [Domain] Long-term Debt, Type [Domain] Loans Payable [Member] Loans Payable [Member] Debt Instrument [Line Items] Other Long-Term Liabilities Schedule of Maturities of Long-term Debt [Table Text Block] Schedule of principal amounts for the loan which the Company is obligated to repay Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of stock option activity Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of stock-based compensation expense Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of assumptions used for the fair values of employee stock options granted Schedule of Nonvested Share Activity [Table Text Block] Summary of restricted stock activity Schedule detailing quantitative information concerning the nature of business and overview of the same. Schedule of Nature of Business and Overview [Table] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event [Member] Nature of Business and Overview [Line Items] Basis of Presentation Investments and Cash Cash, cash equivalents and marketable securities Represents the working capital of the entity. Working Capital Working capital Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] An arrangement whereby an employee, consultant or non-employee director is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. Although there are variations, normally, after vesting, when an option is exercised, the holder pays the strike value in cash to the issuing entity and receives equity shares. The equity shares can be sold into the market for cash at the current market price without restriction. Options may be used to attract, retain and incentivize recipients, in addition to other compensation and other benefits, if any. Employee Consultant And Non Employee Director Stock Option [Member] Employee Consultant and Non Employee Director Stock Option [Member] Restricted Stock [Member] Restricted Stock [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Anti-dilutive securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive Accumulated Other Comprehensive Income (Loss) [Table] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Accumulated Net Unrealized Investment Gain Loss [Member] Accumulated Net Unrealized Investment Gain (Loss) [Member] Accumulated Translation Adjustment [Member] Accumulated Translation Adjustment [Member] Accumulated Other Comprehensive Income (Loss) [Line Items] Comprehensive Income Accumulated Other Comprehensive Income (Loss) [Roll Forward] Changes in accumulated other comprehensive income (loss) by component Reclassification from Accumulated Other Comprehensive Income, Current Period, Net of Tax Amounts reclassified from other comprehensive income Other Comprehensive Income (Loss), before Reclassifications, Net of Tax Other comprehensive income (loss) before reclassifications Other Comprehensive Income (Loss), Net of Tax Net current-period other comprehensive income Fair Value Measurements, Recurring and Nonrecurring [Table] Measurement Frequency [Axis] Fair Value Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Fair Value Measurements Recurring [Member] Fair Value, Measurements, Recurring [Member] Fair Value, Hierarchy [Axis] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Estimate Of Fair Value Fair Value Disclosure [Member] Estimate of Fair Value Measurement [Member] Fair Value Inputs Level2 [Member] Fair Value, Inputs, Level 2 [Member] Fair Value Inputs Level1 [Member] Fair Value, Inputs, Level 1 [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair value measurements Cash and Cash Equivalents, Fair Value Disclosure Money market funds and cash equivalents Available-for-sale Securities Marketable securities Assets, Fair Value Disclosure Total financial assets at fair value Represents the amount of transfer of assets measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Fair Value Assets Amount Transfers between Measurement Levels Assets transferred between the fair value measurement classifications Represents the amount of transfer of liabilities measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Fair Value Liabilities Amount Transfers between Measurement Levels Liabilities transferred between the fair value measurement classifications Schedule of Available-for-sale Securities [Table] Major Types of Debt and Equity Securities [Axis] Major Types Of Debt And Equity Securities [Domain] Major Types of Debt and Equity Securities [Domain] Represents securities issued by US government agencies and municipal governments. U S Government And Municipal Obligations [Member] US Government and Municipal Obligations [Member] Corporate Debt Securities [Member] Corporate Debt Securities [Member] Schedule of Available-for-sale Securities [Line Items] Marketable Securities Available-for-sale Securities, Debt Maturities, Amortized Cost Basis, Fiscal Year Maturity [Abstract] Amortized Cost Available-for-sale Securities, Debt Maturities, Next Twelve Months, Amortized Cost Basis Maturing in one year or less Amount of available-for-sale debt securities at cost, net of adjustments, maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Available For Sale Securities, Debt Maturities after One Through Three Years, Amortized Cost Maturing after one year through three years Available-for-sale Securities, Debt Maturities, Amortized Cost Basis Amortized cost Available-for-sale Securities, Gross Unrealized Gain [Abstract] Gross Unrealized Gains Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities within One Year Gross Unrealized Gain Maturing in one year or less Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Gain Maturing after one year through three years Amount of accumulated unrealized gain before deducting unrealized loss on investments in available-for-sale securities impacting investments. Available For Sale Securities, Gross Unrealized Gain Accumulated in Investments Gross Unrealized Gains Available For Sale Securities, Gross Unrealized Losses [Abstract] Gross Unrealized Losses Represents the gross unrealized losses on securities, at a point in time, which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities within One Year, Gross Unrealized Losses Maturing in one year or less Represents the gross unrealized losses on securities, at a point in time, which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Losses Maturing after one year through three years Amount of accumulated unrealized loss before deducting unrealized gain on investments in available-for-sale securities impacting investments. Available For Sale Securities, Gross Unrealized Loss Accumulated in Investments Gross Unrealized Losses Available-for-sale Securities, Debt Maturities, Fair Value, Fiscal Year Maturity [Abstract] Fair Value Available-for-sale Securities, Debt Maturities, Next Twelve Months, Fair Value Maturing in one year or less Amount of available-for-sale debt securities at fair value maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Available For Sale Securities, Debt Maturities after One Through Three Years, Fair Value Maturing after one year through three years Represents the amount of investment in debt and equity securities considered to be other-than-temporarily impaired, categorized neither as held-to-maturity nor trading. Available For Sale Securities, Considered to be Other than Temporarily Impaired Marketable securities considered to be other-than-temporarily impaired Interest Receivable Accrued interest included in marketable securities Disclosure of the carrying value of purchased amortizable finite-lived intangible assets, including disclosure of the carrying value of indefinite-lived intangible assets not subject to amortization, excluding goodwill, in total and by major class. Finite Lived and Indefinite Lived Intangible Assets by Major Class [Table] Indefinite-lived Intangible Assets [Axis] Indefinite Lived Intangible Assets Major Class Name [Domain] Indefinite-lived Intangible Assets, Major Class Name [Domain] In Process Research And Development [Member] In Process Research and Development [Member] Finite-Lived Intangible Assets by Major Class [Axis] Finite Lived Intangible Assets Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Represents information pertaining to an amendment to the license agreement, Amgen Amendment. Amgen Amendment [Member] Amgen Amendment [Member] Represents information pertaining to the core technology of the entity. Core Technology [Member] Core Technology [Member] Range [Axis] Range [Member] Range [Domain] Minimum [Member] Minimum [Member] Maximum [Member] Maximum [Member] Finite Lived and Indefinite Lived Intangible Assets by Major Class [Line Items] Intangible Assets and Goodwill Indefinite-Lived Intangible Assets (Excluding Goodwill) [Abstract] Indefinite-lived intangible assets: Indefinite-Lived Intangible Assets (Excluding Goodwill) Indefinite-lived intangible assets Finite-Lived Intangible Assets, Net [Abstract] Finite-lived intangible asset Finite-Lived Intangible Asset, Useful Life Estimated Life Finite-Lived Intangible Assets, Gross Cost Finite-Lived Intangible Assets, Accumulated Amortization Accumulated Amortization Finite-Lived Intangible Assets, Net Net Intangible Assets, Net (Excluding Goodwill) [Abstract] Total Intangible Assets Intangible Assets, Gross (Excluding Goodwill) Cost of total intangible assets Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract] Estimated future amortization expense of intangible assets Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months 2014 Finite-Lived Intangible Assets, Amortization Expense, Year Two 2015 Finite-Lived Intangible Assets, Amortization Expense, Year Three 2016 Finite-Lived Intangible Assets, Amortization Expense, Year Four 2017 Finite-Lived Intangible Assets, Amortization Expense, Year Five 2018 Deferred Rent Credit Deferred Rent Deferred Tax Liabilities, Net Net Deferred Tax Liability related to IPR&D Represents the deferred income from the sale of tax benefit. Deferred Income from Sale of Tax Benefits Deferred Income from Sale of Tax Benefits Deferred Revenue Deferred Revenue Other Liabilities Total Represents the value of tax benefits agreed to be sold by the entity during the reporting period. Value of Tax Benefits Agreed to be Sold Amount at which New Jersey tax benefit agreed to be sold Represents the value at which tax benefit sold by the entity during the reporting period. Value at which Tax Benefits Sold Amount of sale of New Jersey tax benefit Represents period for which base of operations must be maintained in New Jersey. Period for which Base of Operations Must be Maintained Period for which base of operations must be maintained Gain (Loss) on Disposition of Other Assets Other income related to sale of tax benefits Loans Payable Loan Payable Other Sundry Liabilities Other Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Type of Arrangement and Non-arrangement Transactions [Axis] Arrangements And Nonarrangement Transactions [Member] Arrangements and Non-arrangement Transactions [Domain] Arrangement under which the entity provides product development services, which may include manufacturing, in return for compensation and/or royalties as agreed between the parties. Product Development And Licensing Agreement [Member] Product Development and Licensing Agreement [Member] Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] REVENUE Represents the estimated cost for the development services under the agreement. Collaborative Arrangement Estimated Cost for Development Services Approved project plan for the development services Represents the term of the collaborative arrangement. Collaborative Arrangement Agreement Term Term of the agreement Represents the amount of upfront payment for development services, which is recorded by the entity as revenue over the term of the agreement. Collaborative Arrangement Upfront Payment Amount Upfront payment recognized as revenue over the term of the agreement Represents percentage of reimbursement of external costs incurred by the company. Reimbursement of external costs incurred percentage Reimbursement of external costs incurred by the company (as a percent) Disclosure of information pertaining to changes in stockholders' equity during the period. Stockholders Equity [Table] A categorization of various plans or programs under which stock of the entity is issued. Stock Issued by Type of Program [Axis] A group of different programs or plans under which stock of the entity is issued. Stock Issued By Type Of Program [Domain] Stock Issued by Type of Program [Domain] Represents the Controlled Equity Offering Program of the entity, as amended, through which shares of common stock may be publicly offered and sold through Cantor Fitzgerald and Co. ("Cantor") in privately negotiated and/or at-the-market transactions. Controlled Equity Offering Program Amended [Member] Controlled Equity Offering Program Amended [Member] Represents the Controlled Equity Offering Program of the entity through which shares of common stock may be publicly offered and sold through Cantor Fitzgerald and Co. ("Cantor") in privately negotiated and/or at-the-market transactions. Controlled Equity Offering Program [Member] Controlled Equity Offering Program [Member] Represents the Shareholder Rights Plan of the entity through which rights issued by the entity entitle recipients to obtain shares of preferred stock of the entity or common stock of an acquiring company. Shareholder Rights Plan [Member] Shareholder Rights Plan [Member] Class of Stock [Axis] Class Of Stock [Domain] Class of Stock [Domain] Series C Preferred Stock [Member] Series C Preferred Stock [Member] Cumulative Preferred Stock [Member] Cumulative Preferred Stock [Member] Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Stockholders Equity [Line Items] Stockholders' Equity Stock Issued During Period, Shares, New Issues Common stock issued (in shares) Stock Issued During Period, Value, New Issues Net proceeds from sale of stock in an underwritten public offering Represents the purchase of additional common stock. Common Stock Exercise of Full over Allotment Option to Purchase Additional Shares by Underwriter Shares issued on exercise of over-allotment option by underwriters (in shares) Represents the common stock available for sale. Common Stock Shares Available For Sale Common stock available for sale (in shares) Represents the aggregate offering price of additional shares which the entity can issue as per amended agreement. Common Stock Issuance of Additional Shares Aggregate Offering Price Aggregate offering price of additional shares which the entity can issue as per amended agreement Represents the fixed commission rate expressed as a percentage of the gross sales price per share of common stock sold by the entity. Fixed Rate of Commission on Sale of Stock Fixed commission rate (as a percent) Represents notice period for termination of agreement. Notice Period for Termination of Agreement Notice period for termination of agreement Represents the lock-up period to be waived by underwriters for remaining aggregate offering price available to the entity for the issuance of common stock as per the amended agreement. Common Stock Available For Sale Lock Up Period to be Waived by Underwriters Lock-up period to be waived by underwriters Represents the maximum value of securities for which the entity filed a shelf registration statement. Shelf Registration Statement Amount Maximum value of securities for which the entity filed a shelf registration statement Warrants and Rights Note Disclosure [Abstract] Shareholder Rights Plan Represents the number of rights that were distributed for each outstanding share of common stock. Class of Warrant or Right, Number of Rights Per Common Stock Share Number of preferred stock purchase rights for each outstanding share of common stock Class of Warrant or Right, Number of Securities Called by Warrants or Rights Number of shares callable by rights Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price (in dollars per unit) Represents the percentage of the entity's outstanding common stock that must be acquired for rights to become exercisable. Class of Warrant or Right Condition on Exercise of Rights Percentage of Common Stock Acquired Percentage of common stock to be acquired for rights to be exercisable Represents the percentage of the entity's outstanding common stock that must be acquired in a tender offer for rights to become exercisable. Class of Warrant or Right Condition on Exercise of Rights Percentage of Common Stock Acquired through Tender Percentage of common stock to be acquired in a tender offer for rights to be exercisable Represents the number of multiples of the exercise price that the right holder has the right to receive in value, if 15 percent or more of the outstanding common stock is acquired. Number of Multiples Class of Warrant or Right Condition on Exercise of Rights of Exercise Price Holder Can Receive in Value if Fifteen Percent or More of Common Stock is Acquired Number of multiples of the exercise price that the Right holder has right to receive in value if 15% or more of the outstanding common stock is acquired Represents the percentage of assets or earning power sold which would allow the right holder the right to receive the common stock of the acquiring entity with a value that is twice the right's exercise price. Class of Warrant or Right Condition on Exercise of Rights Percentage of Assets or Earning Power Sold for Holder Right to Receive Common Stock of Acquiring Company Percentage of assets or earning power sold allowing the Right holder a right to receive common stock of the acquiring company Represents the number of multiples of the exercise price that the right holder has the right to receive in value of the acquiring entity's common stock. Number of Multiples Class of Warrant or Right Condition on Exercise of Rights of Exercise Price Holder Can Receive in Common Stock Value of Acquiring Company Number of multiples of the exercise price that the Right holder has a right to receive in value of the acquiring company's common stock Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Award Type [Axis] Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Equity Award [Domain] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] Represents information pertaining to Celldex Research's 2005 Equity Incentive Plan and CuraGen 2007 Stock Plan of the entity. Celldex Research Equity Incentive Plan2005 And Cura Gen Stock Plan2007 [Member] Celldex Research Equity Incentive Plan 2005 and CuraGen Stock Plan 2007 [Member] Employee Stock [Member] Employee Stock [Member] Represents information pertaining to the 2008 Stock Option and Incentive Plan. Stock Option And Incentive Plan2008 [Member] Stock Option and Incentive Plan 2008 [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Stock-Based Compensation Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Options Outstanding at the end of the period (in shares) Options Outstanding at beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Canceled (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Options Vested and Expected to Vest at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Options Exercisable at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Shares Available for Grant under the 2008 Plan (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price Per Share Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Options Outstanding at the end of the period (in dollars per share) Options Outstanding at beginning of the period (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Canceled (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Options Vested and Expected to Vest at the end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Options Exercisable at the end of the period (in dollars per share) Share Based Compensation Arrangement by Share Based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract] Weighted Average Remaining Contractual Term Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Options Outstanding at the end of the period Options Outstanding at beginning of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Options Vested and Expected to Vest at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Options Exercisable at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Additional General Disclosures [Abstract] Additional information Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant-date fair value (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Fair value of stock options vested (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Aggregate intrinsic value of stock options outstanding (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Aggregate intrinsic value of stock options vested and expected to vest (in dollars) Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Total compensation cost not yet recognized (in dollars) Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Weighted average period over which compensation cost is expected to be recognized as expense Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Total intrinsic value of stock options exercised (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Maximum Number of Shares Per Employee Maximum number of shares of common stock that can be purchased by each participating employee per year Common Stock, Capital Shares Reserved for Future Issuance Common stock reserved for issuance (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent Purchase price as a percentage of the lower of the fair market value of the common stock at either the beginning of the offering period or the applicable exercise date Stock Issued During Period, Shares, Employee Stock Purchase Plans Shares issued under the plan Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Maximum shares of common stock to be issued for grants (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Vesting period The period of time, from the grant date until the time at which the share-based option award expires. Share Based Compensation, Arrangements by Share Based Payment, Award, Options, Expiration Term Terms of options Represents the term of options granted to the holders of more than 10 percent of voting stock of the entity. Share Based Compensation Arrangements by Share Based Payment Award, Options, Expiration Term for Holders of More than Ten Percent of Voting Stock Terms of options granted to the holders of more than 10% of the voting stock Represents the threshold percentage of voting stock. Share Based Compensation, Arrangements by Share Based Payment, Award, Options, Threshold Percentage of Voting Stock Threshold percentage of voting stock Represents the exercise price as a percentage of the fair market for options granted to the holders of than 10 percent of voting stock of the entity. Share Based Compensation Arrangements by Share Based Payment Award, Options, Exercise Price as Percentage of Fair Market Value for Holders of More than Ten Percent of Voting Stock Exercise price as a percentage of fair market value for options granted to the holders of more than 10% of the voting stock Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Shares Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Outstanding and unvested at the end of the period (in shares) Outstanding and unvested at the beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vested (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Canceled (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted Average Grant Date Fair Value (per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Outstanding and unvested at the end of the period (in dollars per share) Outstanding and unvested at the beginning of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Canceled (in dollars per share) Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Research And Development Expense [Member] Research and Development Expense [Member] General And Administrative Expense [Member] General and Administrative Expense [Member] Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] Valuation and Expenses Information Allocated Share-based Compensation Expense Total stock-based compensation expense (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Assumptions used for fair values of employee and director stock options granted Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected stock price volatility (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected option term Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected stock price volatility, minimum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Expected stock price volatility, maximum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, minimum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Risk-free interest rate, maximum (as a percent) Represents the amount of expected dividend payable in foreseeable future. Expected Dividend Payable in Foreseeable Future Expected dividend payable in foreseeable future Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss and tax credit carryforwards, including an assessment of the likelihood of utilization. Operating Loss and Tax Credit Carryforwards [Table] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Internal Revenue Service I R S [Member] Internal Revenue Service (IRS) [Member] State And Local Jurisdiction [Member] State and Local Jurisdiction [Member] Business Acquisition [Axis] Business Acquisition Acquiree [Domain] Business Acquisition, Acquiree [Domain] Represents information pertaining to CuraGen Corporation. Cura Gen Corporation [Member] Cura Gen Corporation [Member] Represents information pertaining to AVANT Immunotherapeutics, Inc. A V A N T [Member] AVANT [Member] Information pertaining to status of merger and acquisition. Status of Merger and Acquisition [Axis] Details of status of merger and acquisition. Status Of Merger And Acquisition [Domain] Status of Merger and Acquisition [Domain] Details prior to merger. Prior To Merger [Member] Prior to Merger [Member] Details prior to acquisition. Prior To Acquisition [Member] Prior to Acquisition [Member] Details pertaining to transactions that result in ownership change as defined by Section 382 of the Internal Revenue Code. Ownership Change [Axis] Transactions that result in ownership change as defined by Section 382 of the Internal Revenue Code. Ownership Change [Domain] Ownership Change [Domain] Details pertaining to ownership change in October 2007. Ownership Change In October2007 [Member] Ownership Change in October2007 [Member] Details pertaining to ownership changes June 2009 and December 2009. Ownership Changes In June2009 And December2009 [Member] Ownership Changes in June 2009 and December 2009 [Member] Tax Credit Carryforward [Axis] Tax Credit Carryforward Name [Domain] Tax Credit Carryforward, Name [Domain] Research [Member] Research Tax Credit Carryforward [Member] Operating Loss and Tax Credit Carryforwards [Line Items] Net operating loss and tax credit carryforwards Number of States in which Entity Operates Number of states in which the entity primarily operates or has operated and has income tax nexus Operating Loss Carryforwards Net operating loss carryforwards The sum of domestic, foreign and state and local operating loss carryforwards, net of expirations and utilization but before tax effects, available to reduce future taxable income under enacted tax laws. Operating Loss Carryforwards Net of Expirations and Utilization NOL, net of expirations and utilization Represents the operating loss carryforwards that were expired during the period. Operating Loss Carryforwards Expired NOLs expired Represents the operating loss carryforwards with limitations on use. Operating Loss Carryforwards with Limitations on Use Loss carryforwards with limitations on use Represents amount of deferred tax assets attributable to deductible operating loss carryforwards not yet utilized. Deferred Tax Assets, Operating Loss Carryforwards not yet Utilized Assets recorded for net operating losses not yet utilized Represents the operating loss carryforwards that are remotely likely to be utilized in future periods. Operating Loss Carryforwards Remotely Likely to be Utilized Loss carryforwards remotely likely to be utilized in future periods Represents the annual limitation on operating loss carryforwards. Operating Loss Carryforwards Annual Limitation Amount Annual limitation Represents the period of recognition of unrealized gain (loss) after ownership change. Period of Recognition of Unrealized Gain (loss) after Ownership Change Period of recognition of unrealized loss or gain after the ownership change Tax Credit Carryforward, Amount Tax credit carryforwards The amount of the tax credit carryforward, with substantial limitations on use before tax effects, available to reduce future taxable income under enacted tax laws. Tax Credit Carryforward Amount with Substantial Limitations on Use Tax credit carryforwards with substantial limitations on use Unrecognized Tax Benefits Unrecognized tax benefits Collaborative Arrangement [Member] Collaborative Arrangement [Member]