Rindopepimut [Member] Rindopepimut Represents the information related to Rindopepimut. PRF Agreement [Member] PRF Details pertaining to the agreement with Paul Royalty Fund II, L.P. (PRF). Rotarix Rotavirus Vaccine [Member] Rotarix Represents the information related to the product Rotarix rotavirus vaccine. Amount Received for Right to Participate in Collaborative Arrangement Upfront fee received Represents the amount received by the entity for the right to participate in a collaborative arrangement. Stock Issued During Period Value Issued for Collaborative Arrangement Equity investment Represents the value of stock sold as an equity investment to obtain the right to participate in a collaborative arrangement. Percentage of License Fee Due on Net Royalties Received Percentage of license fee payable on net royalties received Percentage of license fee payable to third party on net royalties received. Award Type [Axis] Percentage of Interest in Net Royalties Sold Percentage of interest in net royalties sold Represents the percentage of interest in net royalties sold. Period for Right to Negotiate for Extension of Agreement Term Under Certain Circumstances Period for right to negotiate to extend the agreement term Represents the period for right to negotiate for extension of the agreement term under certain circumstances. Number of Multiples Class of Warrant or Right Condition on Exercise of Rights of Exercise Price Holder Can Receive in Common Stock Value of Acquiring Company Number of multiples of the exercise price that the Right holder has a right to receive in value of the acquiring company's common stock Represents the number of multiples of the exercise price that the right holder has the right to receive in value of the acquiring entity's common stock. Stock Option and Incentive Plan 2008 [Member] 2008 Plan Represents information pertaining to the 2008 Stock Option and Incentive Plan. Amendment Description Terms of options The period of time, from the grant date until the time at which the share-based option award expires. Share Based Compensation, Arrangements by Share Based Payment, Award Options, Expiration Term Amendment Flag Share Based Compensation Arrangements by Share Based Payment Award, Options Expiration Term for Holders of More than Ten Percent of Voting Stock Terms of options granted to the holders of more than 10% of the voting stock Represents the term of options granted to the holders of more than 10 percent of voting stock of the entity. Threshold percentage of voting stock Represents the threshold percentage of voting stock. Share Based Compensation, Arrangements by Share Based Payment, Award Options, Threshold Percentage of Voting Stock Share Based Compensation Arrangements by Share Based Payment Award Options Exercise Price as Percentage of Fair Market Value for Holders of More than Ten Percent of Voting Stock Exercise price as a percentage of fair market value for options granted to the holders of more than 10% of the voting stock Represents the exercise price as a percentage of the fair market for options granted to the holders of than 10 percent of voting stock of the entity. License Agreements [Member] License agreements Details pertaining to the license agreements. Medarex Inc [Member] Medarex Represents information related to Medarex, Inc. Rockefeller University [Member] Rockefeller Represents information related to Rockefeller University. Duke University Brain Tumor Cancer Center [Member] Duke Represents information related to Duke University Brain Tumor Cancer Center. Arrangements and Non-arrangement Transactions [Domain] Nature of Business and Overview [Line Items] Basis of Presentation Patent Costs Policy [Text Block] Patent Costs Disclosure of accounting policy for patent costs. Other Income [Policy Text Block] Other Income Disclosure of accounting policy for recognition of income due to transactions that are not part of on-going operations. Basis of Presentation [Abstract] Basis of Presentation Glaxo Represents information related to Glaxo SmithKline plc. Glaxo Smith Kline Plc [Member] Pfizer Inc [Member] Pfizer Represents information related to Pfizer Inc. Laboratory Equipment [Member] Laboratory equipment Details pertaining to laboratory equipment. Laboratory Equipment Manufacturing Equipment [Member] Manufacturing equipment Details pertaining to manufacturing equipment. Manufacturing Equipment Cura Gen Corporation [Member] CuraGen Represents information pertaining to CuraGen Corporation. Current Fiscal Year End Date Debt Instrument Principal Amount Denomination for Conversion into Common Stock Principal amount of notes used for debt instrument conversion ratio The principal amount of notes used as denominator for purposes of computing the conversion ratio of convertible debt. Accrued Royalty and License Fees Current Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties and licenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Royalty and License Fees Accrued Research and Development Contract Costs, Current Accrued Research and Development Contract Costs Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development contract costs. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Debt Instrument Amortization Period Amortization period Represents the amortization period of the debt instrument. Document and Entity Information Product Development and Licensing Agreements Revenue from Product Development and Licensing Agreements This element represents revenue from product development and licensing agreements. Product development and licensing agreement revenue Contracts and Grants Revenue from Contracts and Grants This element represents revenue earned during the period arising from products sold or services provided under the terms of a contract. Also include revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. REVENUE Significant Revenue Arrangements Disclosure [Text Block] This element may be used to capture the complete disclosure pertaining to an entity's significant revenue contracts and arrangements. REVENUE COLLABORATION AGREEMENTS Working Capital Working capital Represents the working capital of the entity. Document Period End Date Finite Lived and Indefinite Lived Intangible Assets by Major Class [Table] Disclosure of the carrying value of purchased amortizable finite-lived intangible assets, including disclosure of the carrying value of indefinite-lived intangible assets not subject to amortization, excluding goodwill, in total and by major class. In Process Research and Development [Member] IPR&D Represents information pertaining to in-process research and development. Amgen Amendment [Member] Amgen Amendment Represents information pertaining to an amendment to the license agreement, Amgen Amendment. Core Technology [Member] Core Technology Represents information pertaining to the core technology of the entity. Identification of the lender, who may be a single entity (for example, a bank, pension fund or venture capital firm) or a group of entities which participate in the debt instrument. Debt Instrument Lender [Domain] MidCap Financial LLC [Member] MidCap Represents information pertaining to MidCap Financial, LLC. Stock Issued by Type of Program [Domain] A group of different programs or plans under which stock of the entity is issued. Controlled Equity Offering Program [Member] Cantor Agreement Represents the Controlled Equity Offering Program of the entity through which shares of common stock may be publicly offered and sold through Cantor Fitzgerald and Co. ("Cantor") in privately negotiated and/or at-the-market transactions. Controlled Equity Offering Program Amended [Member] Represents the Controlled Equity Offering Program of the entity, as amended, through which shares of common stock may be publicly offered and sold through Cantor Fitzgerald and Co. ("Cantor") in privately negotiated and/or at-the-market transactions. Cantor Amendment Shareholder Rights Plan [Member] Represents the Shareholder Rights Plan of the entity through which rights issued by the entity entitle recipients to obtain shares of preferred stock of the entity or common stock of an acquiring company. Shareholder Rights Plan General Electric Capital Corporation [Member] GECC Represents information pertaining to General Electric Capital Corporation. Finite Lived and Indefinite Lived Intangible Assets by Major Class [Line Items] Intangible Assets and Goodwill Intangible Assets, Gross Excluding Goodwill Cost of total intangible assets Sum of the gross carrying amounts before accumulated amortization of all intangible assets, excluding goodwill, as of the balance sheet date. The aggregate gross carrying amount (including any previously recognized impairment charges) of a major finite-lived and indefinite lived intangible asset class. Cost of total intangible assets Tabular disclosure of other long-term liabilities, not separately disclosed on the balance sheet. Schedule of Other Long Term Liabilities [Table Text Block] Schedule of Other long-term liabilities Deferred Income from Sale of Tax Benefits Deferred Income from Sale of Tax Benefits Represents the deferred income from the sale of tax benefit. Amount at which New Jersey tax benefit agreed to be sold Represents the value of tax benefits agreed to be sold by the entity during the reporting period. Value of Tax Benefits Agreed to be Sold Gain (Loss) on Sale of Tax Benefits Gain (loss) on sale of New Jersey tax benefits Represents gain loss on sale of New Jersey tax benefits. Period for which base of operations must be maintained Represents period for which base of operations must be maintained in New Jersey. Period for which Base of Operations Must be Maintained Debt Instrument Lender [Axis] The information pertaining to the debt instrument by lender. Stock Issued by Type of Program [Axis] A categorization of various plans or programs under which stock of the entity is issued. Debt Instrument, Interest Only Period of Extension Extension of interest-only period The period of extension of interest-only period which was extended through exercise of an option for extension by the entity during the reporting period. Upfront fee due upon repayment of the Term Loan in full Represents the upfront fee due upon amendment to extend the maturity period of the Term loan. Debt Instrument up Front Fee Due upon Repayment for Extension of Maturity Period of Debt Debt Instrument, Additional Fee Due on Repayment for Extension of Maturity Period of Debt Additional Final Payment Fee due upon repayment of the Term Loan in full Represents the additional fee due upon repayment of the Term Loan for the extension of the maturity period of debt. Debt Instrument, Payment Fee Payable on Repayment Original Payment Fee payable upon repayment of term loan in full Represents the original payment fee to be paid upon repayment of the Term Loan in full. Available-for-sale Securities, Gross Unrealized Gains Gross Unrealized Gains Debt Instrument, Number of Equal Consecutive Monthly Installments Number of equal consecutive monthly installments Represents the number of equal consecutive monthly installments over which the loan is to be paid. Debt Instrument, Covenant Rate of Prepayment Premium in Year Three Rate of prepayment premium in year three (as a percent) Represents the percentage of prepayment premium of the Term Loan to be paid in year three. Debt Instrument, Covenant Rate of Prepayment Premium in Year Two Rate of prepayment premium in year two (as a percent) Represents the percentage of prepayment premium of Term Loan to be paid in year two. Maximum Rate of Commission on Sale of Stock Rate of commission of gross proceeds on each sale, maximum (as a percent) Represents the rate of commission on sale of stock. Notice Period for Termination of Agreement Notice period for termination of agreement Represents notice period for termination of agreement. Common Stock Exercise of Full over Allotment Option to Purchase Additional Shares by Underwriter Shares issued on exercise of over-allotment option by underwriters (in shares) Represents the purchase of additional common stock. Share Based Compensation Arrangement by Share Based Payment Award Options Weighted Average Remaining Contractual Term [Abstract] Weighted Average Remaining Contractual Term Stockholders Equity [Table] Disclosure of information pertaining to changes in stockholders' equity during the period. Stockholders Equity [Line Items] Stockholders' Equity Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Represents securities issued by US government agencies and municipal governments. U.S. government and municipal obligations US Government and Municipal Obligations [Member] Available For Sale Securities, Debt Maturities after One Through Three Years, Amortized Cost Maturing after one year through three years Amount of available-for-sale debt securities at cost, net of adjustments, maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Available For Sale Securities, Gross Unrealized Gain [Abstract] Gross Unrealized Gains Available For Sale Securities, Debt Maturities within One Year Gross Unrealized Gain Maturing in one year or less Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Gain Maturing after one year through three years Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Maturing in one year or less Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature within the next rolling 12 months following the latest balance sheet presented, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities Next Rolling Twelve Months Gross, Unrealized Gain Available For Sale Securities Debt, Maturities Rolling Year, Two Through Three Gross, Unrealized Gain Represents the gross unrealized gains on securities, at a point in time, which are for those securities which are expected to mature in the second rolling twelve months through the third rolling twelve months following the latest balance sheet presented, and which are categorized neither as held-to-maturity nor as trading securities. Maturing after one year through three years Gross Unrealized Losses Available For Sale Securities, Gross Unrealized Losses [Abstract] Represents the gross unrealized losses on securities, at a point in time, which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities within One Year, Gross Unrealized Losses Maturing in one year or less Represents the gross unrealized losses on securities, at a point in time, which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Losses Maturing after one year through three years Available For Sale Securities, Debt Maturities Next Rolling Twelve Months Gross, Unrealized Losses Maturing in one year or less Represents the gross unrealized losses on securities, at a point in time, for those securities which are expected to mature within the next rolling 12 months following the latest balance sheet presented, and which are categorized neither as held-to-maturity nor as trading securities. Represents the gross unrealized losses on securities, at a point in time, which are expected to mature in the second rolling twelve months through the third rolling twelve months following the latest balance sheet presented, and which are categorized neither as held-to-maturity nor as trading securities. Maturing after one year through three years Available For Sale Securities Debt Maturities, Rolling Year Two Through Three Gross, Unrealized Losses Available For Sale Securities, Debt Maturities after One Through Three Years, Fair Value Maturing after one year through three years Amount of available-for-sale debt securities at fair value maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Amount of available-for-sale debt securities at cost, net of adjustments, maturing in the second rolling twelve months through the third rolling twelve months following the latest balance sheet presented. Adjustments include, but are not limited to, accretion, amortization, collection of cash, previous other-than-temporary impairments (OTTI) recognized in earnings (less any cumulative-effect adjustments, as defined) and fair value hedge accounting adjustments. Maturing after one year through three years Available For Sale Securities, Debt Maturities Rolling Year, Two Through Three Amortized Cost Basis Amount of available-for-sale debt securities at fair value maturing in the second rolling twelve months through the third rolling twelve months following the latest balance sheet presented. Maturing after one year through three years Available For Sale Securities, Debt Maturities Rolling Year Two Through Three, Fair Value Gross Unrealized Gains, rolling maturity Available For Sale Securities, Gross Unrealized Gain Rolling Maturity [Abstract] Available For Sale Securities, Gross Unrealized Losses Rolling Maturity [Abstract] Gross Unrealized Losses, rolling maturity Fixed Rate of Commission on Sale of Stock Fixed commission rate (as a percent) Represents the fixed commission rate expressed as a percentage of the gross sales price per share of common stock sold by the entity. Common Stock Issuance of Additional Shares Aggregate Offering Price Aggregate offering price of additional shares which the entity can issue as per amended agreement Represents the aggregate offering price of additional shares which the entity can issue as per amended agreement. Common Stock Available for Sale Aggregate Offering Price Remaining aggregate offering price available under the Cantor Amendment Represents the remaining aggregate offering price available to the entity for the issuance of common stock as per amended agreement. Significant Accounting Policies Schedule of Nature of Business and Overview [Table] Schedule detailing quantitative information concerning the nature of business and overview of the same. Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent Maximum contribution by participants (as a percent) Maximum percentage of employee gross pay the employee may contribute to a defined contribution plan. Entity Well-known Seasoned Issuer Represents the maximum value of securities for which the entity filed a shelf registration statement. Shelf Registration Statement Amount Maximum value of securities for which the entity filed a shelf registration statement Entity Voluntary Filers Class of Warrant or Right, Number of Rights Per Common Stock Share Number of preferred stock purchase rights for each outstanding share of common stock Represents the number of rights that were distributed for each outstanding share of common stock. Entity Current Reporting Status Class of Warrant or Right Condition on Exercise of Rights Percentage of Common Stock Acquired Percentage of common stock to be acquired for rights to be exercisable Represents the percentage of the entity's outstanding common stock that must be acquired for rights to become exercisable. Entity Filer Category Class of Warrant or Right Condition on Exercise of Rights Percentage of Common Stock Acquired through Tender Percentage of common stock to be acquired in a tender offer for rights to be exercisable Represents the percentage of the entity's outstanding common stock that must be acquired in a tender offer for rights to become exercisable. Entity Public Float Represents the number of multiples of the exercise price that the right holder has the right to receive in value, if 15 percent or more of the outstanding common stock is acquired. Number of Multiples Class of Warrant or Right Condition on Exercise of Rights of Exercise Price Holder Can Receive in Value if Fifteen Percent or More of Common Stock is Acquired Number of multiples of the exercise price that the Right holder has right to receive in value if 15% or more of the outstanding common stock is acquired Entity Registrant Name Class of Warrant or Right Condition on Exercise of Rights Percentage of Assets or Earning Power Sold for Holder Right to Receive Common Stock of Acquiring Company Percentage of assets or earning power sold allowing the Right holder a right to receive common stock of the acquiring company Represents the percentage of assets or earning power sold which would allow the right holder the right to receive the common stock of the acquiring entity with a value that is twice the right's exercise price. Entity Central Index Key Ludwig Institute for Cancer Research [Member] Ludwig Represents information related to Ludwig Institute for Cancer Research. Alteris Represents information related to Alteris Therapeutics, Inc. Alteris Therapeutics Inc [Member] TJU Represents information related to Thomas Jefferson University. Thomas Jefferson University [Member] University of Southampton UK [Member] Southampton Represents information related to University of Southampton, UK. Entity Common Stock, Shares Outstanding Amgen Inc [Member] Amgen Represents information related to Amgen Inc. Represents information related to Seattle Genetics, Inc. Seattle Genetic Inc [Member] Seattle Genetics Non Refundable License Fee Nonrefundable license fee expense Represents the amount of nonrefundable license fee expense. Collaborative Arrangement Royalty Payment Period from First Commercial Sale of Licensed Product Period from the first commercial sale of licensed product for royalty payment Represents the period from the first commercial sale of licensed product for royalty payment under the collaborative arrangement. Collaborative Arrangement, Total Potential Milestone Payments Milestone payment due Represents the total amount of potential milestone payments to be made by the entity based on terms of the collaborative arrangement. Term of the agreement Represents the term of the collaborative arrangement. Collaborative Arrangement Agreement Term Collaborative Arrangement, Number of Agreements Number of exclusive license agreements Represents the number of exclusive license agreements under the collaborative arrangement. Income Tax Reconciliation Expiration of Net Operating Losses and Research and Development Tax Credits Expiration of Net Operating Losses and Research & Development Tax Credits The portion of the difference between total income tax expense or benefit as reported in the Income Statement and the expected income tax expense or benefit computed by applying the domestic federal statutory income tax rates to pretax income from continuing operations attributable to expiration of net operating losses and research and development tax credits under enacted tax laws during the period. Accounts and Other Receivables, Net, Current Accounts and Other Receivables Deferred Tax Liabilities Other Acquired Intangible Assets Other Acquired Intangibles Amount of deferred tax liability attributable to taxable temporary differences from other acquired intangible assets. Deferred Tax Liabilities, Deferred Licence Costs and Other Expense Deferred License Costs and Other Amount of deferred tax liability attributable to taxable temporary differences from license costs and other items that are not separately disclosed. Deferred Tax Assets (Liabilities) Gross Total Deferred Tax Assets and Liabilities Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards, net of deferred tax liability attributable to taxable temporary differences. Amount of deferred tax liability attributable to taxable temporary differences from in-process research and development intangible assets. Deferred Tax Assets in Process Research and Development Intangible Assets IPR&D Intangibles Collaborative Arrangement Milestone Payments Received Other income related to milestone payment received Represents the payment received towards potential commercial milestone payments related to future net sales of Belinostat. AVANT [Member] Represents information pertaining to AVANT Immunotherapeutics, Inc. AVANT Net operating loss and tax credit carryforwards Operating Loss and Tax Credit Carryforwards [Line Items] Represents the annual limitation on operating loss carryforwards. Operating Loss Carryforwards Annual Limitation Amount Annual limitation Operating Loss Carryforwards Expired Represents the operating loss carryforwards that were expired during the period. NOLs expired Document Fiscal Year Focus Operating Loss Carryforwards Net of Expirations and Utilization The sum of domestic, foreign and state and local operating loss carryforwards, net of expirations and utilization but before tax effects, available to reduce future taxable income under enacted tax laws. NOL, net of expirations and utilization Document Fiscal Period Focus Operating Loss Carryforwards with Limitations on Use Represents the operating loss carryforwards with limitations on use. Loss carryforwards with limitations on use Operating Loss Carryforwards Remotely Likely to be Utilized Represents the operating loss carryforwards that are remotely likely to be utilized in future periods. Loss carryforwards remotely likely to be utilized in future periods Ownership Change [Axis] Details pertaining to transactions that result in ownership change as defined by Section 382 of the Internal Revenue Code. Ownership Change [Domain] Transactions that result in ownership change as defined by Section 382 of the Internal Revenue Code. Ownership Change in October2007 [Member] Details pertaining to ownership change in October 2007. Ownership change in October 2007 Ownership Changes in June2009 and December2009 [Member] Details pertaining to ownership changes June 2009 and December 2009. Ownership changes in June 2009 and December 2009 Period of Recognition of Unrealized Gain (loss) after Ownership Change Represents the period of recognition of unrealized gain (loss) after ownership change. Period of recognition of unrealized loss or gain after the ownership change Prior to Acquisition [Member] Details prior to acquisition. Prior to acquisition Prior to Merger [Member] Details prior to merger. Prior to merger Status of Merger and Acquisition [Axis] Information pertaining to status of merger and acquisition. Status of Merger and Acquisition [Domain] Details of status of merger and acquisition. Tax Credit Carryforward Amount with Substantial Limitations on Use The amount of the tax credit carryforward, with substantial limitations on use before tax effects, available to reduce future taxable income under enacted tax laws. Tax credit carryforwards with substantial limitations on use Document Type Operating Loss and Tax Credit Carryforwards [Table] Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss and tax credit carryforwards, including an assessment of the likelihood of utilization. Collaborative Arrangement for Development and Commercialization of Product [Member] Collaboration arrangement for development and commercialization of oral rotavirus strain Details pertaining to collaboration arrangement for development and commercialization of product. Royalty Agreement [Member] Royalty Agreement Details pertaining to royalty agreement. Cincinnati Children's Hospital Medical Center [Member] Cincinnati Children's Hospital Medical Center Represents information related to Cincinnati Children's Hospital Medical Center. Represents information related to Duke University and Thomas Jefferson University. Duke University and Thomas Jefferson University [Member] Duke University and Thomas Jefferson University Common Stock Shares Available For Sale Common stock available for sale (in shares) Expiration of Net Operating Losses and Research and Development Tax Credits Reflects the amounts of net operating losses and research and development tax credits expired during the period. Expiration of Net Operating Losses and Research & Development Tax Credits Common Stock Available for Sale Lock Up Period to be Waived by Underwriters Lock-up period to be waived by underwriters Represents the lock-up period to be waived by underwriters for remaining aggregate offering price available to the entity for the issuance of common stock as per the amended agreement. Represents the value at which tax benefit sold by the entity during the reporting period. Value at Which Tax Benefits Sold Amount of sale of New Jersey tax benefit Assets transferred between the fair value measurement classifications Represents the amount of transfer of assets measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Fair Value Assets Amount Transfers between Measurement Levels Fair Value Liabilities Amount Transfers between Measurement Levels Liabilities transferred between the fair value measurement classifications Represents the amount of transfer of liabilities measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Represents the amount of investment in debt and equity securities considered to be other-than-temporarily impaired, categorized neither as held-to-maturity nor trading. Available for Sale Securities Considered to be Other than Temporarily Impaired Marketable securities considered to be other-than-temporarily impaired Debt Instrument Covenant Rate of Prepayment Premium in Year Four Rate of prepayment premium in year four (as a percent) Represents the percentage of prepayment premium on the term loan to be paid in year four. Accumulated Other Comprehensive Income Loss [Table] Disclosure of information about components of accumulated other comprehensive income (loss). Accumulated Other Comprehensive Income Loss [Table] Accumulated Other Comprehensive Income Loss [Line Items] Accumulated Other Comprehensive Income Loss [Line Items] Comprehensive Income Other comprehensive income (loss) before reclassifications Amount after tax, before reclassification adjustments of other comprehensive income (loss). Other Comprehensive Income Loss Before Reclassifications Net of Tax Other Comprehensive Income Loss Before Reclassifications Net of Tax Reclassification from Accumulated Other Comprehensive Income Current Period Net of Tax Amounts reclassified from other comprehensive income Amount after tax of reclassification adjustments of other comprehensive income (loss). Reclassification from Accumulated Other Comprehensive Income Current Period Net of Tax Accumulated Other Comprehensive Income Loss [Roll Forward] Changes in accumulated other comprehensive income (loss) by component Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] ACCRUED EXPENSES Accounts Payable, Current Accounts Payable Accretion (Amortization) of Discounts and Premiums, Investments Amortization and Premium of Marketable Securities Accrued Professional Fees Accrued Professional Fees, Current Accrued Liabilities, Current Accrued Expenses Accrued Expenses Net unrealized gain related to foreign currency translation included in accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Foreign Currency Translation Adjustment, Net of Tax Unrealized Gain (Loss) on Marketable Securities, net of tax Accumulated Net Unrealized Investment Gain (Loss) [Member] Accumulated Other Comprehensive Income Accumulated Other Comprehensive Income (Loss) [Member] Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less Accumulated Depreciation and Amortization Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income Balance at the beginning of the period Balance at the end of the period Accumulated Translation Adjustment [Member] Foreign Currency Items Additional Paid in Capital, Common Stock Additional Paid-In Capital Additional Paid-In Capital Additional Paid-in Capital [Member] Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities: Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Share-Based Compensation Allocated Share-based Compensation Expense Total stock-based compensation expense (in dollars) Amortization of Intangible Assets Amortization of Acquired Intangible Assets Amortization of Intangible Assets Amortization expense for intangible assets Amortization of Debt Discount (Premium) Non-Cash Interest Expense Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Anti-dilutive securities Net loss per share Antidilutive Securities, Name [Domain] Antidilutive Securities [Axis] Assets, Fair Value Disclosure Total financial assets at fair value Assets, Current [Abstract] Current Assets: Assets [Abstract] ASSETS Assets, Current Total Current Assets Assets. Total Assets Available-for-sale Securities, Debt Securities, Current Marketable Securities Fair Value Available-for-sale Securities, Fair Value Disclosure Marketable securities Available-for-sale Securities, Debt Maturities, Next Rolling Twelve Months, Fair Value Maturing in one year or less Available-for-sale Securities, Debt Maturities, Next Twelve Months, Fair Value Maturing in one year or less Available-for-sale Securities, Debt Maturities, Amortized Cost Basis, Fiscal Year Maturity [Abstract] Amortized Cost Available-for-sale Securities, Debt Maturities, Next Twelve Months, Amortized Cost Basis Maturing in one year or less Available-for-sale Securities, Debt Maturities, Fair Value, Fiscal Year Maturity [Abstract] Fair Value Available-for-sale Securities, Gross Unrealized Losses Gross Unrealized Losses Available-for-sale Securities, Debt Maturities, Fair Value, Rolling Maturity [Abstract] Fair Value, rolling maturity Available-for-sale Securities, Debt Maturities, Amortized Cost Basis Amortized cost Available-for-sale Securities, Debt Maturities, Next Rolling Twelve Months, Amortized Cost Basis Maturing in one year or less Available-for-sale Securities, Debt Maturities, Amortized Cost Basis, Rolling Maturity [Abstract] Amortized Cost, rolling maturity Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Basis of Accounting [Text Block] Basis of Presentation Business Acquisition [Axis] Business Acquisition, Acquiree [Domain] BUSINESS COMBINATIONS Acquisition of CuraGen Corporation Business Acquisition [Line Items] Business Combination Disclosure [Text Block] BUSINESS COMBINATIONS Business Combinations Business Combinations Policy [Policy Text Block] Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents Cash and Cash Equivalents at Beginning of Period Cash and Cash Equivalents at End of Period Cash Acquired from Acquisition Cash Acquired in the CuraGen acquisition Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents, Fair Value Disclosure Money market funds and cash equivalents Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental Disclosure of Non-Cash Flow Information Exercise price (in dollars per unit) Class of Warrant or Right, Exercise Price of Warrants or Rights Class of Stock [Domain] Number of shares callable by rights Class of Warrant or Right, Number of Securities Called by Warrants or Rights Collaboration Agreements Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] REVENUE Collaborative Arrangement Disclosure [Text Block] COLLABORATION AGREEMENTS Collaborative Arrangements and Non-collaborative Arrangement Transactions [Domain] Collaborative Arrangements and Non-collaborative Arrangements [Axis] Commitments and Contingent Liabilities Commitments and Contingencies Disclosure [Text Block] Commitments and Contingent Liabilities Commitments and Contingencies Commitments and Contingent Liabilities (Note 13) Common Stock Common Stock [Member] Common Stock, Shares, Outstanding Common Stock, Shares Outstanding Common Stock, Value, Issued Common Stock, $.001 Par Value; 297,000,000 Shares Authorized; 80,870,320 and 64,359,513 Shares Issued and Outstanding at March 31, 2013 and December 31, 2012, respectively Common Stock, Shares, Issued Common Stock, Shares Issued Balance (in shares) Balance (in shares) Common stock issued (in shares) Common Stock, Par or Stated Value Per Share Common Stock, Par Value (in dollars per share) Common Stock, Shares Authorized Common Stock, Shares Authorized Common stock reserved for issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance RETIREMENT SAVINGS PLAN Components of Deferred Tax Assets and Liabilities [Abstract] Principal components of the deferred tax assets and liabilities Comprehensive Loss COMPREHENSIVE INCOME: Comprehensive Loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent 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