CONDENSED CONSOLIDATED BALANCE SHEETS Statement [Table] Statement, Scenario [Axis] Scenario, Unspecified [Domain] Statement [Line Items] Statement Assets [Abstract] ASSETS Assets, Current [Abstract] Current Assets: Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents Cash and Cash Equivalents at Beginning of Period Cash and Cash Equivalents at End of Period Marketable Securities, Current Marketable Securities Accounts, Notes, Loans and Financing Receivable, Net, Current Accounts and Other Receivables Assets, Current Total Current Assets Property, Plant and Equipment, Net Property and Equipment, Net Intangible Assets, Net (Excluding Goodwill) Intangible Assets, Net Other Assets, Noncurrent Other Assets Goodwill Goodwill Assets. Total Assets Liabilities and Stockholders' Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities, Current [Abstract] Current Liabilities: Accounts Payable, Current Accounts Payable Accrued Liabilities, Current Accrued Expenses Deferred Revenue, Current Current Portion of Deferred Revenue Convertible Subordinated Debt, Current Convertible Subordinated Debt Liabilities, Current Total Current Liabilities Deferred Revenue, Noncurrent Deferred Revenue Convertible Subordinated Debt, Noncurrent Convertible Subordinated Debt Other Liabilities, Noncurrent Other Long-Term Liabilities Liabilities Total Liabilities Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Stockholders' Equity: Common Stock, Value, Issued Common Stock, $.001 Par Value; 297,000,000 Shares Authorized; 44,147,214 and 32,055,382 Shares Issued and Outstanding at June 30, 2011 and December 31, 2010, respectively Common Stock, Shares Authorized Common Stock, Shares Authorized Common Stock, Shares, Issued Common Stock, Shares Issued Common Stock, Shares, Outstanding Common Stock, Shares Outstanding CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS Revenues [Abstract] REVENUE: Product Development and Licensing Agreements Revenue from Product Development and Licensing Agreements This element represents revenue from product development and licensing agreements. Contracts and Grants Revenue from Contracts and Grants This element represents revenue earned during the period arising from products sold or services provided under the terms of a contract. Also include revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. Royalty Revenue Product Royalties Revenues Total Revenue Additional Paid in Capital, Common Stock Additional Paid-In Capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income Retained Earnings (Accumulated Deficit) Accumulated Deficit Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest Total Stockholders' Equity Liabilities and Stockholders' Equity. Total Liabilities and Stockholders' Equity Preferred Stock, Par or Stated Value Per Share Convertible Preferred Stock, Par Value (in dollars per share) Common Stock, Par or Stated Value Per Share Common Stock, Par Value (in dollars per share) Research and Development Expense Research and Development Royalty Expense Royalty General and Administrative Expense General and Administrative Amortization of Intangible Assets Amortization of Acquired Intangible Assets Amortization of Intangible Assets Operating Income (Loss) Operating Loss Interest Expense Interest Expense Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net Loss Net Loss Weighted Average Number of Shares Outstanding, Basic Shares Used in Calculating Basic Net Loss per Share (Note 4) (in shares) CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities [Abstract] Cash Flows from Operating Activities: Depreciation, Depletion and Amortization Depreciation and Amortization Marketable Securities, Gain (Loss) Realized Loss on Sales and Maturities of Marketable Securities Share-based Compensation Stock-Based Compensation Expense Increase (Decrease) in Operating Capital [Abstract] Changes in Operating Assets and Liabilities: Increase (Decrease) in Accounts and Other Receivables Accounts and Other Receivables Increase (Decrease) in Other Operating Assets Other Assets Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts Payable and Accrued Expenses Increase (Decrease) in Deferred Revenue Deferred Revenue Increase (Decrease) in Other Operating Liabilities Other Long-Term Liabilities Net Cash Provided by (Used in) Operating Activities Net Cash Used in Operating Activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash Flows from Investing Activities: Proceeds from Sale and Maturity of Marketable Securities Sales and Maturities of Marketable Securities Payments to Acquire Marketable Securities Purchases of Marketable Securities Payments to Acquire Property, Plant, and Equipment Acquisition of Property and Equipment Net Cash Provided by (Used in) Investing Activities Net Cash Used in Investing Activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash Flows from Financing Activities: Proceeds from Issuance of Common Stock Net Proceeds from Stock Issuances Net Cash Provided by (Used in) Financing Activities Net Cash Provided by Financing Activities Effect of Exchange Rate on Cash and Cash Equivalents Effect of Exchange Rate Changes on Cash and Cash Equivalents Cash and Cash Equivalents, Period Increase (Decrease) Net Decrease in Cash and Cash Equivalents Document and Entity Information Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Comprehensive Income Note [Text Block] Comprehensive Loss Earnings Per Share [Text Block] Net Loss Per Share Fair Value Disclosures [Text Block] Fair Value Measurements Marketable Securities [Text Block] Marketable Securities Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Goodwill and Intangible Assets Disclosure [Text Block] Intangible Assets and Goodwill Income Tax Disclosure [Text Block] Income Taxes Significant Revenue Arrangements Long-term Debt [Text Block] Term Loan Preferred Stock, Value, Issued Convertible Preferred Stock, $.01 Par Value; 3,000,000 Shares Authorized; No Shares Issued and Outstanding at June 30, 2011 and December 31, 2010 Preferred Stock, Shares Authorized Convertible Preferred Stock, Shares Authorized Preferred Stock, Shares Issued Convertible Preferred Stock, Shares Issued Preferred Stock, Shares Outstanding Convertible Preferred Stock, Shares Outstanding Non-Cash Interest Expense Paid-in-Kind Interest Increase (Decrease) in Prepaid, Deferred Expense and Other Assets Prepaid and Other Current Assets Proceeds from Sale of Productive Assets Proceeds from Sale or Disposal of Assets Repayments of Other Long-term Debt Payments of Other Long-Term Liabilities Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental Disclosure of Non-Cash Flow Information Stock Issued Significant Accounting Policies Schedule of New Accounting Pronouncements and Changes in Accounting Principles [Text Block] This element represents all significant accounting policies of the reporting entity. Also includes disclosure of any changes in an accounting principle, including a change from one generally accepted accounting principle to another generally accepted accounting principle when there are two or more generally accepted accounting principles that apply or when the accounting principle formerly used is no longer generally accepted. Also disclose any change in the method of applying an accounting principle, or any change in an accounting principle required by a new pronouncement in the unusual instance that a new pronouncement does not include specific transition provisions. Significant Accounting Policies Significant Revenue Arrangements Disclosure [Text Block] This element may be used to capture the complete disclosure pertaining to an entity's significant revenue contracts and arrangements. Significant Revenue Arrangements Business Combination Disclosure [Text Block] CuraGen Acquisition Costs and Expenses [Abstract] OPERATING EXPENSE: Gain (Loss) on Disposition of Assets Gain on Sale of Assets Costs and Expenses Total Operating Expense Nonoperating Income (Expense) Investment and Other Income, Net Weighted Average Number of Shares Outstanding, Diluted Shares Used in Calculating Diluted Net Loss per Share (Note 4) (in shares) Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities: Accretion (Amortization) of Discounts and Premiums, Investments Amortization and Premium of Marketable Securities Gain (Loss) on Sale of Property Plant Equipment (Gain) Loss on Sale or Disposal of Assets Stockholders' Equity Note Disclosure [Text Block] Stockholders' Equity Stock Granted During Period, Value, Share-based Compensation Shares Issued to Executive Officers Other Liabilities, Current Current Portion of Long-Term Liabilities Amortization of Debt Discount (Premium) Non-Cash Interest Expense Other Liabilities Disclosure [Text Block] Other Long-Term Liabilities Current Portion of Term Loan Secured Debt, Current Term Loan, less Current Portion Secured Long Term Debt Proceeds from Issuance of Long-term Debt Issuance of Term Loan Repayments of Subordinated Debt Payment of Convertible Subordinated Debt Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Amendment Description Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Filer Category Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Period Focus Prepaid Expense and Other Assets Current Prepaid and Other Current Assets Commitments and Contingencies Commitments and Contingent Liabilities Basis of Presentation Net Loss Per Share Fair Value Measurements Marketable Securities Intangible Assets and Goodwill Term Loan Other Long-Term Liabilities